Seinfeld is NOT a show that I would ever in a million years look to for inspiration.
I loved the show, but the characters were shallow, selfish and not really people I would want to hang out with, well, Krammer maybe I would like to hang with.
That said, I have always thought that George Costanza was onto something when he realized that his life was not what he had envisioned. He came to the conclusion that everything he had ever done had been wrong and that all his decisions were wrong. So he started doing the opposite of everything that made sense to him.
I really think that if you do that in moderation in regards to certain decisions in life that good things can come of it. I know personally some of my decisions have been terrible, I should have gone against the grain and done the opposite.